Tuesday, June 15, 2010

Thyroid nodules Management dilemma

Introduction:
Thyroid nodule is a common occurrence. Majority of these nodules may be present without clinical evidence of thyroid disease. Statistics reveal that the incidence of palpable thyroid nodule is about 5%. Ultrasound neck is very sensitive in picking up thyroid nodules. Ultrasound can diagnose thyroid nodules even as small as ½ cm. Studies have shown that only 3-5% of thyroid nodules show malignant transformation.

Causes of thyroid nodules include:

Benign causes:

1.Goitre
2.Hashimoto's thyroiditis
3.Simple / hemorrhagic cysts
4.Follicular adenoma
5.Subacute thyroiditis

Malignant causes:

1.Papillary carcinoma
2.Follicular carcinoma
3.Hurthle cell carcinoma
4.Medullary carcinoma
5.Anaplastic carcinoma
6.Primary thyroid lymphoma
7.Metastatic malignant lesion

Tools of diagnosis as far as these thyroid nodules include:

1.Ultrasound neck
2.FNAC
3.Molecular / genetic marker analysis of fine needle aspiration biopsies





Image showing ultrasound of a benign looking thyroid nodule





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2 comments:

kaney said...

A thyroid disease is a condition that causes the thyroid gland which is located within our neck to function abnormally producing either too little or too much of the thyroid hormones that are essential for the regulation of our body's metabolism. The thyroid gland is prone to numerous diseases and disorders that can cause hyperthyroidism which is the overproduction of thyroid hormones and hypothyroidism which is the underproduction of thyroid hormones.

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Piotr GoĊ‚ofit said...

The lesion depicted on the image does not look benign.